2025 Clinical Practice Guideline for the Pharmacologic Management of Adults with Dyslipidemia

This guideline was developed by a multidisciplinary task force and uses the GRADE framework to provide evidence-based recommendations regarding cardiovascular risk assessment, benefits and harms of newer medications, and treatment goals with a focus on patient-important outcomes.

Guideline: AACE Members-Only Advanced Viewing

This AACE clinical guidance document and commentary are available exclusively to AACE members and Endocrine Practice subscribers February 5-11. They will be publicly accessible on February 12, 2025.

Read Guideline

 

Commentary: AACE Members-Only Advanced Viewing

Review highlights and commentary from practicing endocrinologist and immediate past chair of the AACE CPG Oversight Committee, Dr. Ricardo Correa, on the updated AACE guideline for dyslipidemia.

Read Commentary

 


Patient Summary

Use this patient-friendly summary of the guideline to help with shared decision-making with your patients to better understand the treatment options for reducing lipids and their risk of heart disease.

Share Patient Summary

 


AACE Podcasts Episode 57: 2025 AACE Dyslipidemia Guideline Overview

Join Dr. David Lieb as he moderates an engaging discussion with Dr. Shailendra Patel, Chair of the Dyslipidemia Guideline Task Force, and Dr. Kathleen Wyne, Vice Chair, about the recently released 2025 AACE Clinical Practice Guideline on Pharmacologic Management of Adults with Dyslipidemia.

This episode covers:

  • What’s new or different in this update compared to the 2017 guideline.
  • Surprising insights revealed during the evidence assessments and how they shaped the recommendations.
  • Key considerations for clinicians as they integrate these updated recommendations into practice.
  • Gaps in the literature and opportunities for future research.

Whether you’re familiar with the previous guideline or new to this topic, this conversation provides a comprehensive overview of the latest advancements in dyslipidemia management.


AACE Podcasts Episode 58: 2025 AACE Dyslipidemia Guideline Methodology

In this episode, join moderator Dr. David Lieb alongside esteemed panelists Dr. Shahnaz Sultan, Dr. Carol Peng, and Dr. Melanie Bird as they delve into the methodology behind the 2025 AACE Clinical Practice Guideline on Pharmacologic Management of Adults with Dyslipidemia.

Discover insights into:

  • Why AACE adopted the GRADE framework and its implications for guideline development.
  • The critical role of systematic reviews in creating evidence-based recommendations.
  • How evidence is assessed using the GRADE approach.
  • Practical takeaways for clinicians when implementing GRADE-informed guidelines in patient care.

Whether you’re a seasoned practitioner or new to the field, this discussion offers valuable perspectives on the evolution of evidence-based guideline development and its impact on clinical practice.