Clinical Guidance

2025 Consensus Statement on Management of Multiple Endocrine Neoplasia, Type 1

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
Podcasts
This AACE consensus statement was developed by a multidisciplinary task force, which included medical professionals in endocrinology, endocrine surgery, surgical oncology, genetics, and clinical research as well as a patient representative, who conducted a targeted review of the literature to provide practical patient-centered clinical guidance for practitioners who care for individuals with MEN1.

2023 AACE Consensus Statement: Comprehensive Type 2 Diabetes Management Algorithm

Diabetes
Algorithms
Consensus Statements
Podcasts
This algorithm provides concise visual guidance in the form of algorithms to assist with clinical decision-making for the management of persons with type 2 diabetes mellitus and related comorbidities.

2023 AACE Consensus Statement: Addressing Stigma and Bias in the Diagnosis and Management of Patients with Obesity/Adiposity-Based Chronic Disease and Assessing Bias and Stigmatization as Determinants of Disease Severity

Nutrition and Obesity
Consensus Statements
Podcasts
This new consensus statement summarizes important areas of agreement around the topics of obesity stigma and weight bias from the perspectives of the individual, clinicians, and the healthcare system following the May 2022 AACE Consensus Conference on improving obesity outcomes.

2022 Consensus Statement on Immune Checkpoint Inhibitor-Mediated Endocrinopathies

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This consensus statement provides a practical approach for management of patients with immune checkpoint inhibitor (ICI)-mediated endocrinopathies with case scenarios of various clinical manifestations and highlights the role of the endocrinology team in the multidisciplinary management of ICI-induced endocrinopathies. The statement summarizes the use of ICI (anti-CTLA-4, anti-PD1, and anti-PD-L1) therapies; reviews the clinical presentation of ICI-related endocrinopathies; and discusses the diagnosis and management approaches to endocrinopathies related to ICI therapy.

2022 Consensus Statement on Minimally Invasive Procedures for Benign and Malignant Thyroid Lesions

Thyroid
Consensus Statements
This consensus statement provides information on novel minimally invasive therapeutic interventions for thyroid malignancies such as percutaneous ethanol injection and thermal ablation. The statement summarizes existing knowledge and provides guidance on indications, techniques, complications, and follow-ups for care of patients with benign and malignant thyroid lesions.

2021 Consensus Statement on Pediatric Benign and Malignant Thyroid Surgery

Thyroid
Co-sponsored Clinical Guidance
Consensus Statements
This consensus statement outlines expert opinion and practical information on the evaluation of thyroid nodules, surgical considerations, and postoperative monitoring for children and adolescents with benign and malignant thyroid lesions.

2021 Consensus Statement on Thyroid Nodule Algorithmic Tool

Thyroid
Algorithms
Co-sponsored Clinical Guidance
Consensus Statements
This consensus statement describes the Thyroid Nodule App (termed TNAPP), a novel interactive web-based tool that uses clinical, imaging, cytologic, and molecular marker data to guide clinical decision making to evaluate and manage thyroid nodules.

2020 Consensus Statement on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This consensus statement provides a practical approach to management of patients with newly diagnosed adrenocortical carcinoma, as well as follow-up and management of patients with persistent or recurrent disease, including the management of an adrenal mass, presurgical evaluation, surgical approach, pathologic assessment, and other therapeutic modalities, based on individual patient presentation.

2020 Algorithm on the Management of Dyslipidemia and Prevention of Cardiovascular Disease

Cardiometabolic and Lipids
Algorithms
Consensus Statements
This algorithm for the comprehensive management of dyslipidemia and prevention of cardiovascular disease (CVD) complements the 2017 AACE Guideline for Management of Dyslipidemia and Prevention of Cardiovascular Disease and provides clinicians with a practical guide that considers the whole patient, their spectrum of risks and complications, and evidence-based approaches to treatment.

2019 Consensus Statement on the Evaluation of Incidentally Discovered Adrenal Masses

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This consensus statement provides a practical approach to the evaluation of incidentally discovered adrenal masses, presenting five patient case scenarios selected to highlight a unique and relatively characteristic presentation that clinicians may encounter and answering key questions to help guide evaluation, diagnosis, management, and treatment.

2018 Consensus Statement on the Quality of DXA Scans and Reports

Bone and Parathyroid
Consensus Statements
This consensus statement identifies common technical errors and issues that can affect DXA report conclusions and provides guidance on how to address those issues to ensure that patients receive appropriate osteoporosis care.

2017 Consensus Statement on Transgender Medicine

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
These six case discussions present clinical vignettes to illustrate some of the key recommendations for diagnosis, treatment, and long-term management of transgender children and adults in the Endocrine Society's 2017 guideline, co-sponsored by AACE, on endocrine treatment of persons with gender dysphoria/gender incongruence.

2015 Consensus Statement for Pre-Operative Therapy in Management of Patients with Acromegaly

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This statement addresses the use of somatostatin-receptor ligands (SRLs) as preoperative therapy for individuals with acromegaly to improve outcomes.

2015 Consensus Statement on Macroprolactin

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This statement addresses the prevalence of macroprolactin in patients with hyperprolactinemia and macroprolactin’s relevance regarding clinical decision-making about laboratory testing, imaging, and pharmacologic or surgical treatment.

2015 Consensus Statement on Traumatic Brain Injury

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This statement addresses neuroendocrine evaluation, testing, and management of patients with traumatic brain injury‒induced hypopituitarism or those at risk for hypopituitarism.

2015 Consensus Statement on MEN Thyroidectomy

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This statement employs case studies to discuss evaluation, early diagnosis, surgical treatment, and ongoing management of endocrinopathies in patients with multiple endocrine neoplasia, type 2.

2015 Consensus Statement on Midgut Carcinoids

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
Carcinoid tumors, which most commonly originate from the small intestine, are either referred to as small intestinal neuroendocrine tumors or midgut carcinoids. This statement addresses diagnostics and therapeutics for patients with midgut carcinoids and provides an overview of multidisciplinary care to improve quality of life, treatment outcomes, and survival.

2015 Consensus Statement on Pancreatic Incidentalomas

Pituitary, Gonad, Adrenal and Neuroendocrine
Consensus Statements
This statement addresses incidental detection of pancreatic neuroendocrine tumors, imaging-based characterization for differential diagnoses, prognosis, and appropriate management.

2013 Consensus Statement on the Clinical Approach to the Detection of Lipodystrophy

Cardiometabolic and Lipids
Consensus Statements
Lipodystrophy is a rare, heterogeneous group of syndromes characterized by the complete or partial loss or absence of subcutaneous adipose tissue. This consensus statement provides an overview of the literature and expert opinion on recognizing lipodystrophy and some potential management strategies.