Clinical Guidance

2025 Clinical Practice Guideline for the Pharmacologic Management of Adults with Dyslipidemia

Cardiometabolic and Lipids
Clinical Practice Guidelines
Podcasts
This guideline was developed by a multidisciplinary task force and uses the GRADE framework to provide evidence-based recommendations regarding cardiovascular risk assessment, benefits and harms of newer medications, and treatment goals with a focus on patient-important outcomes.

AvoMD Integrates AACE Clinical Guidance Documents

Bone and Parathyroid
Cardiometabolic and Lipids
Diabetes
Nutrition and Obesity
Pituitary, Gonad, Adrenal and Neuroendocrine
Thyroid
Clinical Practice Guidelines

AvoMD, a software platform that brings clinical evidence into the workflow to help clinicians streamline decisions and save time, has partnered with AACE to integrate clinical guidance documents into the AvoMD platform. This partnership provides endocrinologists, primary care physicians, nurse practitioners, physician assistants/physician associates, and dietitians with seamless access to evidence-based endocrinology recommendations at the point-of-care.

2022 Clinical Practice Guideline for Development of a Diabetes Mellitus Comprehensive Care Plan

Diabetes
Clinical Practice Guidelines
Podcasts
This updated guideline provides recommendations for the care and management of people with or at risk for diabetes mellitus at every stage, including prevention, diagnosis, and treatment.

2022 Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings

Cardiometabolic and Lipids
Algorithms
Clinical Practice Guidelines
Co-sponsored Clinical Guidance
Podcasts
This guideline provides evidence-based recommendations regarding the diagnosis and management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) to endocrinologists, primary care clinicians, health care professionals, and other stakeholders.

2021 Clinical Practice Guideline for the Use of Advanced Technology in the Management of Persons with Diabetes Mellitus

Diabetes
Clinical Practice Guidelines
Podcasts
Advanced diabetes technology can potentially assist persons with diabetes to achieve glycemic targets, improve quality of life, reduce burden of care, offer a personalized approach to self-management, and improve the efficiency of clinical decision-making, among other benefits. This guideline provides recommendations on the efficacy and safety of advanced diabetes technology devices for management of persons with diabetes mellitus, metrics used to aide with the assessment of advanced diabetes technology, and standards for implementation of this technology.

2020 Clinical Practice Guideline for the Diagnosis and Treatment of Postmenopausal Osteoporosis

Bone and Parathyroid
Algorithms
Clinical Practice Guidelines
Podcasts
This guideline provides recommendations to reduce a person's risk of osteoporosis-related fractures and to evaluate, diagnose, and treat osteoporosis in postmenopausal women, based on fracture presence, assessment of fracture risk/probability, measurement of bone mineral density or bone mass, and a patient’s history, among other factors. An update of this guideline is currently in development.

2019 Clinical Practice Guideline for Management of Growth Hormone Deficiency in Adults and Patients Transitioning from Pediatric to Adult Care

Pituitary, Gonad, Adrenal and Neuroendocrine
Clinical Practice Guidelines
Podcasts
This guideline provides recommendations on identification, screening, assessment, diagnosis, and treatment of a range of individuals with various causes of adult growth-hormone deficiency (GHD) and patients with childhood-onset GHD transitioning to adult care. The guideline summarizes current knowledge about the accuracy of available GH–stimulation tests, safety of recombinant human GH (rhGH) replacement, unapproved uses of rhGH related to sports and aging, and new developments such as long-acting GH preparations that use a variety of technologies to prolong GH action.

2019 Clinical Practice Guideline for the Perioperative Nutrition, Metabolic, and Nonsurgical Support of Patients Undergoing Bariatric Procedures

Nutrition and Obesity
Clinical Practice Guidelines
Co-sponsored Clinical Guidance
Podcasts
This guideline identifies patient candidates for bariatric procedures, discusses which types of bariatric procedures should be offered, outlines management of patients before procedures, and recommends how to optimize patient care during and after procedures.

2017 Endocrine Society Clinical Practice Guideline on Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons

Pituitary, Gonad, Adrenal and Neuroendocrine
Clinical Practice Guidelines
Co-sponsored Clinical Guidance
This 2017 guideline‒led by the Endocrine Society and co-sponsored with AACE, American Society of Andrology, European Society for Pediatric Endocrinology, European Society of Endocrinology, Pediatric Endocrine Society, and World Professional Association for Transgender Health‒is an update of the 2009 Endocrine Society guideline on endocrine treatment of transsexual persons. An update of this guideline is in development.

2016 Clinical Practice Guideline and Algorithm for Medical Care of Patients with Obesity

Nutrition and Obesity
Algorithms
Clinical Practice Guidelines
The 2016 guideline and algorithm address key aspects of obesity care: screening, diagnosis, clinical evaluation, treatment options, therapy selection, and treatment goals.

2016 Clinical Practice Guideline for the Diagnosis and Management of Thyroid Nodules

Thyroid
Clinical Practice Guidelines
Co-sponsored Clinical Guidance
This clinical practice guideline covers diagnostic and therapeutic aspects of thyroid nodular disease but not thyroid cancer management.

2012 Clinical Practice Guideline for Hypothyroidism in Adults

Thyroid
Clinical Practice Guidelines
Co-sponsored Clinical Guidance
This guideline provides recommendations for diagnosis and clinical management of patients with hypothyroidism in the ambulatory care setting.

2011 Clinical Practice Guideline for Hyperthyroidism and Other Causes of Thyrotoxicosis

Thyroid
Clinical Practice Guidelines
Co-sponsored Clinical Guidance
This guideline provides evidence-based recommendations for the management of patients with thyrotoxicosis.