Scientific Articles

Preparing for the NASH Epidemic: A Call to Action

In this article, 32 experts in gastroenterology, hepatology, endocrinology, and primary care providers, identified the promising approaches for clinical practice and prepared a comprehensive, unified strategy for primary care providers and relevant specialists encompassing the full spectrum of NAFLD/NASH care.

Associations Between Vitamin D and Microvascular Complications in Middle-Aged and Elderly Diabetic Patients

The objective of the cross-sectional study was to investigate the association of serum 25-hydroxyvitamin D levels with estimated glomerular filtration rate, albuminuria/creatinine ratio and the prevalence of diabetic retinopathy in Chinese diabetic adults.

Exposure to the Chinese Famine in Early Life and the Thyroid Function and Nodules in Adulthood

Previous studies found famine exposure was associated with a higher risk of metabolic syndrome and fatty liver in adult women. In this study, we investigated the relationship between the Chinese famine exposure in early life and the thyroid function and nodules in adulthood.

Effect of Age and Gender on Fasting and Food-Stimulated Levels of Calcitonin, Parathyroid, and Gastrin Hormones in Healthy Adults

This study was to investigate the effect of age and gender on basal and food-stimulated serum calcitonin, parathyroid hormone, and gastrin levels among healthy adults.

Exposure to Famine in Early Life and the Risk of Osteoporosis in Adulthood: A Prospective Study

The purpose of this study was to assess the association between famine exposure in early life and osteoporosis in adulthood.

The Management of Hyperglycemia in Non-critically Ill Hospitalized Patients Treated With Continuous Enteral and Parenteral Nutrition

The development of hyperglycemia during parenteral and enteral nutrition therapy increases the risks of hospital-related complications and mortality. This review aims to discuss the pathogenesis of hyperglycemia from artificial nutrition in the hospital, summarize current evidence on the treatment of hyperglycemia with insulin in these patients, and review current guidelines.

Waist Circumference and Subclinical Thyroid Dysfunction in a Large Cohort of Chinese Men and Women

The association between subclinical thyroid dysfunction and waist circumference is controversial, especially from the perspective of sex differences. We aimed to explore the impact of sex on this relationship in a large Chinese cohort.

Iodine Nutrition in the Republic of Artsakh (Nagorno Karabakh)

The mountainous terrain in the Republic of Artsakh (Nagorno Karabakh) in the south Caucasus suggests that it is likely to be endogenously deficient in iodine. Since 2005, iodine is a government-sanctioned compulsory supplemental ingredient in salt in Armenia. However, there has never been a study of iodine nutrition in Artsakh. We sought to determine the level of iodine nutrition in Artsakh and the iodine content of table salt in the region.

Impact of Weight Loss Trajectory Following Randomization to Bariatric Surgery on Long-Term Diabetes Glycemic and Cardiometabolic Parameters

It's unclear whether acute weight loss or the chronic trajectory of weight loss after bariatric surgery is associated with long-term type-2 diabetes glycemic improvement. This ancillary study of the STAMPEDE trial aims to answer this question.

Fatty Kidney Disease: A New Renal and Endocrine Clinical Entity? Describing the Role of the Kidney in Obesity, Metabolic Syndrome and Type-2 Diabetes

The purpose of this study was to determine whether fatty kidney disease deserves to be designated as a distinct clinical entity similar to fatty liver disease.

Greater Combined Reductions in HBA1C ≥1.0% and Weight ≥5.0% With Semaglutide vs. Comparators in Type-2 Diabetes

In the global SUSTAIN clinical trial program, semaglutide demonstrated superior HbA1c and body weight reductions vs comparators. This post hoc analysis compared the proportion of patients achieving combined reductions in glycemia and body weight vs comparators.

Association Between the Serum Uric Acid Level and the Body Mass Index in Sex- and Age-Specific Groups in Southwestern China

This study was to investigate the sex- and age-specific association between the serum uric acid level and the body mass index.

Goals for Medical Treatment in Obesity and Prediabetes: Improving Outcomes for Both

The purpose of this review is to expose the surprising prevalence of diabetes-related complications in people with persistent prediabetes, and hence, to expand the paradigm of diabetes prevention to include the prevention of complications related to both hyperglycemia and obesity.

Provider Practice Habits and Barriers to Care in Obesity Management in a Large Multi-center Health System

This study sought to identify provider recommendations and barriers in obesity management in a multi-center academic health system with extensive weight-loss management resources.

Application of the AACE/ACE Advanced Framework for the Diagnosis of Obesity and Cardiometabolic Disease Staging in a General Population From 3 Regions of Venezuela: The Vemsols Study Results

The purpose of this study was to determine the prevalence of obesity according to the AACE/ACE framework based on a complications-centric model with further application of the Cardiometabolic Disease Staging system in a Venezuelan population.

Total Body Adiposity, Triglycerides, and Leg Fat Are Independent Risk Factors for Diabetic Peripheral Neuropathy in Chinese Patients With Type-2 Diabetes Mellitus

The purpose of this study was to evaluate the risk factors associated with diabetic peripheral neuropathy in Chinese patients with type-2 diabetes mellitus.

DPP4 Inhibitor Sitagliptin as a Potential Treatment Options in Metformin-Intolerant Obese Women With Polycystic Ovary Syndrome: A Pilot Randomized Study

Metformin has an established role in the management of polycystic ovary syndrome (PCOS). Some patients cannot tolerate it due to associated gastrointestinal adverse events. The present study evaluated the dipeptidyl peptidase 4 inhibitor sitagliptin as a potential treatment option in metformin-intolerant PCOS.

Increased Bone Turnover in Type-2 Diabetes Patients Randomized to Bariatric Surgery Versus Medical Therapy at 5 Years

The aim of this study was to determine the 5-year outcomes of bariatric surgery versus intensive medical therapy on bone turnover in patients with type 2 diabetes mellitus (T2DM) from the STAMPEDE trial.

Adiposity-Based Chronic Disease as a New Diagnostic Term (2017)

AACE and ACE introduce Adiposity-Based Chronic Disease (ABCD) as a new diagnostic term for obesity that identifies a chronic disease, alludes to a precise pathophysiologic basis, and avoids the stigmata and confusion related to the differential use and multiple meanings of the term “obesity.”

AACE Clinical Case Reports

Access a wide range of case reports, visual vignettes and commentary from noted endocrinology experts.

Endocrine Practice - the Journal for Clinical Endocrinology

Endocrine Practice, our official journal, keeps you on the leading edge of endocrine patient care.

Position Statement on the Advanced Framework for a New Diagnosis of Obesity as a Chronic Disease (2014)

Resulting from the 2014 AACE/ACE Consensus Conference on Obesity, this position statement offers an advanced framework for a new diagnosis of obesity as a chronic disease, a new diagnostic algorithm, and recommendations on the diagnosis and management of obesity.