AACE Medical Guidelines for Clinical Practice for Diagnosis and Treatment of Menopause © 2011

This consensus document will present recommendations for the use of MHT for the relief of menopausal symptoms. It will consider the possible role of MHT in the prevention of chronic disorders associated with estrogen deficiency. Moreover, it will assess the benefit-versus-risk profile of MHT, including our current understanding of the effects of MHT on multiple organ systems. The target audience is endocrinologists, nonendocrinologist physicians, and interested laypersons. Evidence presented in these guidelines was obtained through MEDLINE searches and available references compiled by guideline chairs and task force members. In addition, expert opinion was used to evaluate the available scientific literature, which was graded for treatment recommendations by evidence-based medicine guidelines (2 [EL 4;NE]) and then presented in specific references in the appended reference list.